Alectinib vs Crizotinib in ALK NSCLC: Final ALEX Data
Alectinib vs Crizotinib in ALK NSCLC: Final ALEX Data
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The ALK inhibitor crizotinib was shown to be superior to platinum-based chemotherapy as first-line therapy for NSCLC; subsequent trials showed that second-generation agents were superior to crizotinib. But despite improved efficacy, drug resistance and recurrent disease — including CNS progression, a major cause of illness and death — still develop. New research findings are summarized in a short video. https://nej.md/2Il1OUi | The New England Journal of Medicine
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Dr Nieva on the Rationale for Comparing ALK Inhibitors in ALK NSCLC | OncLive
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