Daily Mini Been is Here! Dopaminergic pathways, sometimes called dopaminergic projections, are the sets of projection neurons in the brain that synthesize and release the neurotransmitter dopamine. There are four dopaminergic pathways. Dr.Mobeen Syed explains, that from the midbrain to the limbic system especially nucleus accumbens, is the mesolimbic pathway. (Abnormality in this pathway causes schizophrenia). D2 receptors are present. The mesocortical pathway between the midbrain and frontal lo