It is a remarkable time for the development of CRISPR-based therapies. In late 2023, we saw the first-ever approval of CRISPR-based medicine: Casgevy, a cure for sickle cell disease (SCD) and …

In this review, we attempt to identify trends in clinical studies involving CRISPR techniques to gain insights into the improvement and contribution of CRISPR/Cas technologies compared to traditional …

Sep 16, 2025 · CRISPR-GPT, a large language model developed at Stanford Medicine, is accelerating gene-editing processes and increasing accessibility to CRISPR. Stanford Medicine researchers have …

Oct 1, 2024 · One such study involving delivery of CRISPR/Cas components using lipid nanoparticles was conducted by Jessica Seitzer, in which gene knockout was done in case of hereditary …

In this review, we first outline the molecular architecture and mechanistic basis of CRISPR-Cas9 and then consider its latest applications in modeling, drug screening, small-molecule-mediated editing, …

As of February 2025, CRISPR Medicine News monitors approximately 250 clinical trials involving gene-editing therapeutic candidates, with more than 150 trials currently active.

Dec 5, 2025 · The human body is capable of mutating a single gene to produce a wide range of debilitating disorders. Genomic editing for disease prevention via phenotypic reversal was a …

Jul 31, 2025 · This issue highlights several cutting-edge developments in CRISPR–Cas9 research. Ruis et al. explore the molecular repair mechanisms of DNA breaks induced by CRISPR–Cas9.

We first introduce the CRISPR system and explain how it works as a gene editing tool. We then highlight current and potential clinical uses of CRISPR in areas such as genetic disorders, infectious diseases, …

Nov 21, 2024 · The review underscores the burgeoning interest in CRISPR-based interventions. Current trials barely tap CRISPR's potential for treating genetic diseases.