Researchers identify genetic variants and patterns associated with hypermobile Ehlers–Danlos syndrome

Hypermobile Ehlers-Danlos syndrome (hEDS) is one of the most common heritable connective tissue disorders. Early estimates have reported that this genetic disorder affects at least one in 5,000 ...

RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Researchers are embarking on the RNA equivalent of the Human Genome Project, including sequencing all the chemical modifications that make cells unique.

DeepChopper model improves RNA sequencing research by mitigating chimera artifacts

Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more ...

New tool cracks microbial defense codes for faster, precise bioengineering

Scientists at the Department of Energy's Oak Ridge National Laboratory have developed software that reduces the time needed ...
Frontiers

A finite element analysis on the execution effects of two novel distalization sequences in clear aligners

Objective: Current clear aligners have the problem of long treatment duration, and the effect of traditional molar distalization sequences is not ideal. To address these issues, this study proposes a ...
Traders Magazine

FINRA Approves Overhaul of Pattern Day Trading Rules, Opens Doors for Smaller Investors

The Financial Industry Regulatory Authority (FINRA)’s Board of Governors has approved a major overhaul of its pattern day trading (PDT) rules, marking a critical shift in how active retail trading ...
eLife

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing

This is a valuable study that uses single-cell RNA sequencing to define tumor-intrinsic transcriptional programs that characterize distinct types of small intestine neuroendocrine tumors. The evidence ...
eLife

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...
BMJ

AB0227 TREATMENT SEQUENCING PATTERNS AND COMPARATIVE EFFICACY IN PATIENTS WITH RHEUMATOID ARTHRITIS FROM A REAL-WORLD SETTING

3 Icahn School of Medicine at Mount Sinai, Oncology, New York, United States of America 4 Icahn School of Medicine at Mount Sinai, PRECISION MEDICINE, Stamford, United States of America Background The ...