Thrombosis and hemostasis are vital processes preserving vascular health, with disruptions leading to debilitating and life-threatening disorders such as ...

The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can ...

Bacteria are constantly moving with the help of motility organs called flagella or pili to colonize new niches. Also, ...

The studies established the lead asset to be well tolerated in healthy volunteers at all doses with a good safety profileSYT-510 demonstrated penetration in the central nervous system and a pharmacody ...

The studies established the lead asset to be well tolerated in healthy volunteers at all doses with a good safety ...

Immunotherapy has transformed the treatment of cancer, yet many patients do not have response or lasting benefit. Strategies ...

Researchers at the Université de Montréal evaluating the pharmacokinetics and pharmacodynamics of a single oral dose of trazodone in laboratory rabbits determined plasma concentrations of the drug ...

Positive Phase 1 study showed safety, tolerability and a linear pharmacokinetic: pharmacodynamic: efficacy relationship (1: 1: 1)Planning ...

Data support advancement of GS-6791 into clinical testing in patients with inflammatory diseases; first-in-human Phase 1 trial in healthy volunteers is ongoing Data are being presented at the European ...

Novartis AG acquires Tourmaline Bio, Inc. for $1.4B to boost its cardiovascular pipeline with pacibekitug. Click here for more on NVS and TRML stocks.

The findings challenge long-standing assumptions about therapy-related cancers. They also highlight how drug actions can substitute for genetic changes in tumor development. An international team of ...

Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist prescribed for weight loss, to reduce the risk of serious cardiovascular problems, and to treat a serious liver problem called ...