A plant extract altered muscle metabolism in guinea pigs, improving glucose-related processes. Green tea has long been valued ...

The aim was to investigate the long-term effects of metformin ingestion on high-intensity interval training on performance, glycogen concentration (GC), GLUT-4 content, and metabolomics outcomes in ...

Type 2 diabetes (T2D) has become one of the leading chronic diseases worldwide in terms of both incidence and mortality. According to the International Diabetes Federation (IDF), approximately 537 ...

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure. This review synthesizes evidence establishing immune ...

The GLUT4 transporter plays a key role in insulin-induced glucose uptake, which is impaired in insulin resistance. The objective of the present study was to investigate the tissue content and the ...

Our desks keep us glued to chairs for hours, yet our bodies keep score. After meals, our blood sugar spikes, particularly if we remain sedentary. Two fresh studies have now analyzed the respective ...

STONY BROOK, N.Y. — Brain aging follows a surprising trajectory with a potentially game-changing discovery: there appears to be a crucial “window” in middle age when interventions targeting metabolism ...

STANFORD, Calif. — Could the secret to maintaining a youthful, sharp mind be as simple as watching our sugar intake? A new study from Stanford Medicine suggests that glucose plays a surprising role in ...

Summary: Neural stem cells, which create new neurons in the brain, become less active with age due to elevated glucose levels. Researchers found that by knocking out the glucose transporter gene GLUT4 ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The study by Akita B.

Glucose enters the cell through specialized proteins known as glucose transporters, or GLUT transporters. These transporters facilitate the movement of glucose across the cell membrane, which is ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The two clathrin isoforms, CHC17 and CHC22, ...