Gastric cancer (GC) is characterized by highly heterogeneous tumors, whose progression is genetically driven and closely associated with hypoxia and an immunosuppressive tumor microenvironment (TME).

ABSTRACT: Endometriosis (EMs), a prevalent chronic inflammatory disease among women of reproductive age, has a global prevalence of 10% - 15% and is closely associated with 30% - 50% of infertility ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted.

Background: Hypothyroidism is a systemic hypometabolic disorder characterized by thyroid hormone deficiency and is closely associated with oxidative stress. The cAMP/PKA signaling pathway is ...

The Editors of Stroke are issuing an Expression of Concern regarding article, “CCR5 Activation Promotes NLRP1-Dependent Neuronal Pyroptosis via CCR5/PKA/CREB Pathway After Intracerebral Hemorrhage” ...

To explore the effects of arabinoxylan on the BDNF/TrkB/p-CREB signaling pathway in the prefrontal cortex of post-stroke depressed rats, and to explore its neuronal protective effects through the ...

Xcel Energy’s $1.7 billion Colorado Power Pathway transmission project has run into a rough road in Elbert County where the county commissioners Wednesday voted to deny project permits to the state’s ...

Select members of the Wnt family of secreted glycoproteins have been implicated in inducing the myogenic determinant genes Pax3, MyoD and Myf5 during mammalian embryogenesis(1,2), but the mechanism of ...

Stroke causes somatic dysfunction and psychological disorders, leading to poststroke depression (PSD). This study investigates mood alterations in PSD models via cerebellar intermittent theta burst ...