Here we report the creation of a predominantly β-structured mini-protein motif. The design target is based on the naturally occurring toxin hand (TH) motifs that are composed of four disulfide bonds ...

All proteins are made of basic secondary structure units, either α-helix or β-sheets, determined by hydrogen bonding between the amino acids within a peptide chain. On a larger scale, structures are ...

One of the most familiar shapes in science is DNA’s double helix structure. First discovered in 1953, this structure uncovered a wealth of information about our genes and the DNA molecules that encode ...

Scientists have discovered a new DNA structure that is inside human cells and have dubbed the structure "i-motif." I-motif resembles a twisted knot of DNA rather than the double helix were all learned ...

When we think of the structure of DNA, the image that most likely comes to mind is that of the iconic double helix. This shape was identified in 1953 as DNA's most common form, and while other ...

The knot-like i-motif structure protruding from DNA’s double helix has been mapped in 50,000 locations in the human genome, concentrated in key functional areas including regions that control gene ...

Scientists have discovered a new structure inside human cells: a never-before-seen twisted "knot" of DNA. Dubbed the "i-motif," this four-stranded knot looks totally different from the iconic double ...