Previous experience with antiretroviral compounds has indicated that viral replication can be affected through the use of agents that target multiple steps in the HIV lifecycle. Even within the ...

A new study overthrows a long-held theory on how HIV finds its way into host cells. Rather than fusing directly with the host cell membrane, the virus is first engulfed by it to form a vesicle that ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

Over the last few days social media has been filled with wonderful photos and stories of people proudly living with HIV from all around the world as part of the #NormalizeHIVChallenge. Including me.

That assembly and release of HIV-1 particles takes place at the plasma membrane has been established for some time. It has also been suspected that the process additionally requires lipid rafts — ...

A partnership will enable low-cost, generic lenacapavir for HIV prevention in LMICs, aiming to improve access and reduce infections significantly.

Many factors ― including scare tactics in school, agenda-pushing politics and misrepresentations in popular culture ― have created a massive stigma around HIV and AIDS. This impacts everything we ...

Gilead offers a meaningful upside opportunity should it execute on increasing revenue growth to the low-to-middle single ...

The 39th annual event aims to raise $500,000 to support Whitman-Walker’s HIV testing, outreach, prevention, and treatment ...

Over the last few years, a consensus has emerged as to the identity of the cell surface molecules required for infection by HIV-1 (ref. 1). The viral envelope protein first binds to CD4, a protein ...

Interestingly, the anti-HIV-1 targets of triterpene analogs can vary depending on the side chain modification position. C-28 modified betulinic acid analogs are potent HIV entry inhibitors, while C-3 ...