Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...

Decades ago scientists identified a particular class of proteins driving illnesses from cancer to neurodegenerative disease. These “intrinsically disordered proteins” (IDPs) looked different from the ...

LA JOLLA, CA – July 12, 2012 –Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with ...

Similar to Alzheimer's disease, the hereditary disease spinocerebellar ataxia type 17 (SCA17) leads to the destruction of brain nerve cells and the premature death of patients. The exact mechanisms of ...

One new project will examine the nervous system of the octopus, one of several understudied areas funded by the new awards. (UW Photo) The Paul G. Allen Frontiers Group, a division of Seattle’s Allen ...

WALTHAM, Mass.--(BUSINESS WIRE)--Avilar Therapeutics, a biopharmaceutical company focused on extracellular protein degradation, today announced a scientific poster presentation highlighting ATACs ...

In cancer research, it's a common goal to find something about cancer cells -- some sort of molecule -- that drives their ability to survive, and determine if that molecule could be inhibited with a ...

In a new research report, scientists at Johns Hopkins Medicine say they have identified a potential target for drugs that ...