Abstract: Down syndrome, induced by trisomy 21 (T21), manifests as cognitive impairment and significant fetal congenital anomalies. Noninvasive prenatal testing (NIPT) for trisomy 21 involves the ...
Department of Bioengineering, University of California - Los Angeles, Los Angeles, California 90095, United States ...
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The reaction conditions and procedures of the duplex crystal digital RT– PCR (RT–cdPCR) were optimized. The specificity, sensitivity, and repeatability of the developed assay were evaluated. The ...