In a study, blocking the immune system complement protein C3 was shown to reduce MS disease severity in older mice but not in ...

In this analysis of patients with myeloperoxidase-ANCA-positive AAV, all urinary complement C3 fragment levels were elevated significantly compared with healthy controls (P <.01 for all).

Suchandrima Bhowmik has written over 300 articles on various health conditions, medical news, and recent breakthroughs. Her work appears in several publications, including Medical News Today, ...

C3.ai (AI) stock has dropped 59% over the past year to a $2B market cap. The company is down 92% from its peak. C3.ai revenue fell 20% year-over-year to $75.1M. The company burned through $86M in cash ...

The complement system is an innate immune response that leads to increased inflammation. The drug pegcetacoplan—a complement inhibitor—was approved for medical use in the United States in 2021 to ...

Scientists have spotted a new variety of riled-up microglia that drives swelling in the human brain. In the November 18 Neuron, researchers from China led by Haixiao Liu, Shunnan Ge, and Yan Qu at ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

The last time I spoke about Apellis Pharmaceuticals (APLS) it was with respect to an article entitled "Apellis: Rare Kidney Disease Data Leads To Possible First To Market". With respect to this ...

Forbes contributors publish independent expert analyses and insights. Scott Hutcheson teaches leadership at Purdue University. In biology, nothing changes all at once. A single cell fires, a chemical ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...

Background: Molecular events that drive endometriosis (EM) and cause accompanying immune deregulation remain elusive. Our purpose was to identify key pathways involved in lesion formation across ...