Giri et al. present a case report involving a patient with metachronous low-volume metastatic hormone-sensitive prostate cancer (mHSPC) who declined standard treatments such as androgen deprivation ...

The immune-fibrosis axis plays a critical role in cardiac remodeling after acute myocardial infarction. Imaging approaches to monitor temporal inflammation and fibroblast activation in mice have seen ...

Current pretargeting systems use noncovalent biologic interactions, which are prone to immunogenicity. We previously developed a novel approach based on the bioorthogonal reaction between a ...

PET scans are used in the diagnosis and staging of various cancers, with [18 F]FDG the most widely used radiotracer (1). The glucose analog FDG utilizes the increased glucose demand of many tumors ...

Journal of Nuclear Medicine September 2025, jnumed.125.270807; DOI: https://doi.org/10.2967/jnumed.125.270807 ...

Ultrasound is among the most rapidly advancing imaging techniques. Functional methods such as elastography have been clinically introduced, and tissue characterization is improved by contrast-enhanced ...

Journal of Nuclear Medicine September 2025, jnumed.125.270267; DOI: https://doi.org/10.2967/jnumed.125.270267 ...

Objectives: The aim of this study was to determine the influence of timing of Lu-177 PSMA radioligand therapy (PRLT) in metastatic prostate cancer (mPC). Methods: Out of 512 mPC patients restaged due ...

The latest digital whole-body PET scanners provide a combination of higher sensitivity and improved spatial and timing resolution. We performed a lesion detectability study on two generations of ...

Journal of Nuclear Medicine September 2025, jnumed.125.269688; DOI: https://doi.org/10.2967/jnumed.125.269688 ...

Elevation of the end-tidal partial pressure of CO2 (PETco2) increases cerebral and myocardial blood flow (MBF), suggesting that it may be a suitable alternative to pharmacologic stress or exercise for ...

Intraoperative dual-modality imaging can help the surgeon distinguish tumor from normal tissue. This technique may prove particularly valuable if small tumors need to be removed that are difficult to ...