NMDA receptors are ionotropic glutamate receptors that mediate excitatory neurotransmission and underpin synaptic plasticity, learning and memory. Their unique voltage-dependent block by magnesium and ...

Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated. If cancer arises from cellular mutation, why don't ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

The human brain constantly adapts in response to experiences, forming new connections between neurons and reorganizing ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

Scientists have zeroed in on a critical weak spot behind a rare but devastating brain autoimmune disorder often known as “Brain on Fire.” The disease strikes when the immune system attacks NMDA ...

A new study published in Science Advances describes a potential target for therapies aimed at treating anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, also known as ‘Brain on Fire,’ an ...

Neurons generated from stem cells (from skin fibroblasts) of a patient with sporadic Alzheimer’s disease. Visualized with a specific green fluorescent marker. Nuclei are shown in blue. Researchers ...

Researchers use cryo-EM to reveal how the NMDA receptor's Asn cage filters calcium from magnesium to drive learning and memory.

GRIN Therapeutics' initiates pivotal phase 3 Beeline study of radiprodil for GRIN-related neurodevelopmental disorder: New York Tuesday, May 5, 2026, 17:00 Hrs [IST] GRIN Therapeu ...