Mast cells are centrally implicated in the progression of diabetic kidney disease through their roles in inflammation, fibrotic remodelling and microvascular dysfunction. In the diabetic milieu, ...

The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the immune system that spring into action with histamine-filled granules in response ...

Mast cells are long‐lived, tissue‐resident immune cells derived from the myeloid lineage and strategically positioned at barrier surfaces such as skin, airways and the gastrointestinal tract. Their ...

Mast cells may play a more central role in the development of asthma than previously demonstrated, according to a the study from the Institute of ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect against ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published in Science Translational Medicine. The ...

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

Systemic mastocytosis (SM) is a rare blood disorder in which the body produces too many mast cells. Part of the immune response, mast cells are a type of white blood cell that releases histamine in ...