The interaction between mast cells and other immune cells at sites of allergic responses has been largely unexplored. A research group at the MPI of Immunobiology and Epigenetics used specialized ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown that in mice mast cells function as a sensor ...

Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow. It mainly occurs in older individuals and represents about 20 ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

Mast cell activation syndrome has gained traction on social – but is it being correctly diagnosed? An MCAS expert explains ...

Mast cells may play a more central role in the development of asthma than previously demonstrated, according to a the study from the Institute of ...

Mast cells are tissue-resident immune sentinels best known for their central role in type I hypersensitivity and allergic inflammation. They express high-affinity receptors for immunoglobulin E (IgE), ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists have now shown in mice: mast cells function as a sensor that signals the animals to avoid antigens, ...