For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained ...
To solve a problem, scientists first need to see it clearly. Whether it’s a virus slipping past the immune system or plaques ...
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...
RNA is one of the bodies most vital molecules, and it comes in a few forms. For example, messenger RNA fills an essential role in gene expression by copying the sequences of active genes, which are ...
IGF2BP3 links cancer metabolism and RNA control, offering a potential new therapeutic target for blocking leukemia cell growth.
Research led by a physicist at the University of California, Riverside, shows how viruses form protective shells, or capsids, ...
Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...
Look inside a brain cell with Huntington’s disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...
The metaphors we used to describe DNA make it sound almost sacred. Proteins, too, are revered. They are the “workhorses of the cell.” They make things happen. RNA, by contrast, has not been so exalted ...
Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one ...
As climate change and human activity threaten freshwater ecosystems like lakes and rivers, it’s more important than ever to know how the species who inhabit them are being impacted. But traditional ...