Novak Djokovic lost to Matteo Arnaldi in the opening round of the Madrid Open on Saturday, extending the 24-time Grand Slam winner's struggles on clay ahead of Roland Garros.

On Saturday, the 4-seed Djokovic took on unseeded Matteo Arnaldi in their first-ever meeting. Arnaldi defeated Djokovic in straight sets during their second-round match at the Madrid Open: 6-3, 6-4.

Novak Djokovic has had a lengthy career of dominance. He's won every significant title and has the most Grand Slams of all time. But nothing lasts forever. The Serbian suffered a 6-3, 6-4 loss to Matteo Arnaldi at the Madrid Open on Saturday.